Sarcopenia
The age-related loss of muscle mass and function erodes strength, independence, and resilience — and it is a direct target for restoring regenerative signaling.
Advancing therapeutics for improved human function.
Activome Therapeutics develops gene- and protein-restoration therapies designed to reactivate the body's own capacity for regeneration — targeting sarcopenia, neurodegenerative disease, and the broader decline of function with age.
The company
A pharmaceutical company built around a single, disciplined thesis.
Activome Therapeutics develops therapies designed to restore the molecular regulators of tissue regeneration — the signals that sustain cellular function, and whose decline underlies much of age-related loss of function. Where those signals fail, our aim is to restore them.
We begin with a focused lead program and a company built to carry a broader portfolio as the science advances. Our discipline is deliberate: a clear mechanism, rigorous preclinical work, and a credible path to the clinic.
Lead program
Restoring the regenerative signals that decline with age.
Our lead program is a gene- and protein-restoration therapy designed to restore key regulators of tissue regeneration — the signals that sustain the body's ability to repair itself, and whose loss underlies age-related decline.
Neurodegenerative disease
In Alzheimer's and related disorders, the breakdown of cellular maintenance and repair is central. Restoration offers a clear rationale where options remain limited.
Age-related decline
Beyond any single disease, the broad decline of function with age is the unifying problem Activome is built to address.
Where we are. Activome's programs are in early development and have not been approved by any regulatory authority. See the pipeline.
Approach
A strategy, pursued with discipline.
- Restoration, not management
- We aim to restore the biology that fails with age — not merely to manage its symptoms.
- Mechanism first
- Every program begins with a clear molecular rationale and rigorous preclinical characterization before it advances.
- Built to endure
- We design for durable effect and long-term clinical relevance, rather than transient benefit.
Mission
Addressing the loss of biological function across neurologic and muscular systems.
Activome is built on a conviction: that age-related loss of function is not an immutable fate, but a biological process with identifiable, addressable causes. Restore what declines, and function can follow. Our lead program is the beginning of that work, and our company is structured to pursue it across the systems — cognition, movement, and resilience — where the need is greatest.
Contact
For scientific, partnering, and investment inquiries.
We welcome correspondence from scientists, prospective collaborators, institutional partners, and investors.
Get in touch